Nucynta

Nucynta treats chronic moderate to severe pain. Do not drink alcohol while taking this medication. Do not suddenly stop taking Nucynta. Your doctor will slowly decrease your dose.

Nucynta Overview

Updated: 

Nucynta is a prescription medication used to treat moderate to severe pain that is expected to last for a short period of time. The long-acting tablet form is also used to treat moderate to severe around-the-clock pain and pain from damaged nerves (neuropathic pain) that happens with diabetes. Nucynta belongs to a group of drugs called opioids which work by stopping pain signals made in the brain.

This medication comes as an immediate-release tablet and oral solution forms and is usually taken every 4 to 6 hours, with or without food.

Common side effects of Nucynta are nausea, dizziness, and vomiting. Do not drive a car or operate machinery if you have these symptoms.

Patient Ratings for Nucynta

How was your experience with Nucynta?

First, a little about yourself

Tell us about yourself in a few words?

What tips would you provide a friend before taking Nucynta?

What are you taking Nucynta for?

Choose one
  • Other

How long have you been taking it?

Choose one
  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did Nucynta work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend Nucynta to a friend?

Nucynta Cautionary Labels

precautionsprecautionsprecautionsprecautionsprecautions

Uses of Nucynta

Nucynta is a prescription medication used to treat moderate to severe pain that is expected to last for a short period of time.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Nucynta Drug Class

Nucynta is part of the drug class:

Side Effects of Nucynta

The common side effects with Nucynta are nausea, dizziness, vomiting, sleepiness, and itching.

Constipation is a common side effect of all opioid medicines. Talk to your doctor about the use of laxatives and stool softeners to prevent or treat constipation while taking Nucynta.

These are not all the possible side effects of Nucynta. For a complete list, ask your doctor or pharmacist.

Nucynta Interactions

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Using Nucynta with other medicines can cause serious side effects. The doses of some other medicines may need to be changed. Your doctor can tell you what medicines can be safely taken with Nucynta. 

Especially tell your doctor if you take:

  • Monoamine Oxidase Inhibitors (MAOIs)
  • Any medicine that makes you sleepy. Nucynta can make you sleepy and affect your breathing. Taking these medicines together can be dangerous.

Nucynta Precautions

Nucynta can cause serious side effects including:

  • Life-threatening breathing problems. Call your doctor right away or get emergency medical help if you:
    • have trouble breathing, or have slow or shallow breathing 
    • have a slow heartbeat 
    • have severe sleepiness 
    • have cold, clammy skin 
    • feel faint, dizzy, confused, or can not think, walk or talk normally 
    • have a seizure 
    • have hallucinations
  • Physical Dependence. Nucynta can cause physical dependence. Talk to your doctor about slowly stopping Nucynta to avoid getting sick with withdrawal symptoms. You could become sick with uncomfortable symptoms because your body has become used to the medicine. Tell your doctor if you have any of these symptoms of withdrawal: feeling anxious, sweating, sleep problems, shivering, pain, nausea, tremors, diarrhea, upper respiratory symptoms, hallucinations, hair "standing on end." Physical dependence is not the same as drug addiction. Your doctor can tell you more about the differences between physical dependence and drug addiction. 
  • Serotonin syndrome. Serotonin syndrome is a rare, life-threatening problem that could happen if you take Nucynta with Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin and Norepinephrine Reuptake Inhibitors (SNRIs), Monoamine Oxidase Inhibitors (MAOIs), triptans or certain other medicines. Call your doctor or get medical help right away if you have any one or more of the these symptoms: you feel agitated, have hallucinations, coma, rapid heart beat, feel overheated, loss of coordination, over active reflexes, nausea, vomiting, or diarrhea. 
  • Seizures. Nucynta can cause seizures in people who are at risk for seizures or who have epilepsy. Tell your doctor right away if you have a seizure and stop taking Nucynta.
  • Low blood pressure. This can make you feel dizzy if you get up too fast from sitting or lying down.

Do not drive, operate machinery, or participate in any other possibly dangerous activities until you know how you react to this medicine. Nucynta can make you sleepy. 

Do not take Nucynta if you:

  • have severe asthma, trouble breathing, or other lung problems
  • a bowel blockage or have narrowing of the stomach or intestines.
  • taken a monoamine oxidase inhibitor (MAOI) medicine or have taken a MAOI medicine within the last 14 days.

You should not drink alcohol while using Nucynta. Alcohol increases your chance of having dangerous side effects.

Nucynta Food Interactions

There are no known food interactions with Nucynta.

Inform MD

Nucynta may not be right for you. Tell your doctor about all your medical conditions, including if you have:

  • trouble breathing or lung problems 
  • or had a head injury 
  • liver or kidney problems 
  • convulsions or seizures 
  • dependency problems with alcohol 
  • pancreas or gall bladder problems 
  • past or present substance abuse or drug addiction. There is a risk of abuse or addiction with narcotic pain medicines. If you have abused drugs in the past, you may have a higher chance of developing abuse or addiction again while using Nucynta.
  • are pregnant or plan to become pregnant 
  • are breast-feeding. You should not breast-feed while taking Nucynta.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Using Nucynta with other medicines can cause serious side effects. The doses of some other medicines may need to be changed. Your doctor can tell you what medicines can be safely taken with Nucynta. 

Especially tell your doctor if you take:

  • Monoamine Oxidase Inhibitors (MAOIs). 
  • any medicine that makes you sleepy. Nucynta can make you sleepy and affect your breathing. Taking these medicines together can be dangerous.

Nucynta and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

This medication falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Nucynta and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Because of the potential for adverse reactions in nursing infants from Nucynta, a decision should be made whether to stop nursing or stop the drug.

Nucynta Usage

Oral solution:

  • Do not change your dose. Take Nucynta oral solution exactly as prescribed by your healthcare provider.
  • If you miss a dose of Nucynta oral solution you can take the dose when you remember if you have pain, or you can wait for the next dose.
  • You can take Nucynta oral solution with or without food.
  • Make sure you understand exactly how to measure your dose. Always use the oral syringe provided with your Nucynta oral solution to help make sure you measure the right amount. Call your pharmacist if you have difficulties with measuring your medicine.
  • Call your healthcare provider if the dose you are taking does not control your pain.
  • Do not stop taking Nucynta oral solution without talking to your healthcare provider.
  • After you stop taking Nucynta oral solution, flush any unused oral solution down the toilet.

Immediate-release tablets:

  • Do not change your dose. Take Nucynta exactly as prescribed by your healthcare provider.
  • If you miss a dose of Nucynta you can take the dose when you remember if you have pain, or you can wait for the next dose.
  • You can take Nucynta with or without food.
  • Make sure you understand exactly how to measure your dose. Always use the oral syringe provided with your Nucynta to help make sure you measure the right amount. Call your pharmacist if you have difficulties with measuring your medicine.
  • Call your healthcare provider if the dose you are taking does not control your pain.
  • Do not stop taking Nucynta without talking to your healthcare provider.

Nucynta Overdose

If you take too much this medication, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If this medication is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Never give anyone else your Nucynta. They can be harmed and even die from taking it.
  • Store Nucynta away from children and in a safe place to prevent stealing or abuse.
  • Selling or giving away Nucynta is against the law.