Midodrine is used to treat dizziness that occurs upon sitting up or standing. This medicine is used only when low blood pressure affects daily life and the ability to perform daily activities.

Midodrine Overview

Reviewed: October 2, 2013

Midodrine is a prescription medication used to treat orthostatic hypotension (OH). This medication belongs to a group of drugs called alpha receptor agonists, which help to maintain adequate blood pressure and to prevent symptoms of OH including dizziness or lightheadedness.

This medication comes in tablet form and is taken 3 times a day, with or without food.

Common side effects include tingling sensations, itching, problems with urinating, and stomach pain.

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Uses of Midodrine

Midodrine is a prescription medication used to treat orthostatic hypotension (OH). OH results in dizziness, lightheadedness, or even fainting after standing from a sitting or lying down position.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Midodrine Brand Names

Midodrine may be found in some form under the following brand names:

Midodrine Drug Class

Midodrine is part of the drug class:

Side Effects of Midodrine

Serious side effects have been reported with midodrine.

Common side effects include:

  • tingling
  • itching
  • problems with urinating
  • stomach pain
  • goosebumps
  • chills
  • high blood pressure while at rest

This is not a complete list of midodrine side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Midodrine FDA Warning

Because midodrine hydrochloride tablets can cause marked elevation of supine blood pressure, it should be used in patients whose lives are considerably impaired despite standard clinical care. The indication for use of midodrine hydrochloride tablets in the treatment of symptomatic orthostatic hypotension is based primarily on a change in a surrogate marker of effectiveness, an increase in systolic blood pressure measured one minute after standing, a surrogate marker considered likely to correspond to a clinical benefit. At present, however, clinical benefits of midodrine hydrochloride tablets, principally improved ability to carry out activities of daily living, have not been verified.