Metacam

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Pharmacist Teresa Brucker, PharmD overviews the uses and common side effects of Meloxicam
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Pharmacist Teresa Brucker, PharmD overviews the uses and common side effects of Meloxicam
NSAIDs
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Metacam Overview

Updated: 

Meloxicam is a prescription medication used to relieve the pain and swelling of osteoarthritis and rheumatoid arthritis. Meloxicam belongs to a group of medications called non-steroidal anti-inflammatory drugs (NSAIDs), which work by stopping substances in your body that cause inflammation and pain.

This medication comes in tablet and oral suspension forms and is taken once a day, with or without food.

Common side effects of meloxicam include diarrhea, upset stomach, and upper respiratory infections.

Meloxicam can cause dizziness. Do not drive or operate heavy machinery until you know how meloxicam will affect you.

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  • Osteoarthritis

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Metacam Cautionary Labels

precautionsprecautionsprecautionsprecautionsprecautionsprecautions

Uses of Metacam

Meloxicam is a prescription medication used to relieve symptoms of:

  • osteoarthritis (arthritis from the damage of joint linings)
  • rheumatoid arthritis (arthritis from the swelling of joint linings)
  • juvenile rheumatoid arthritis in children 2 years of age and older

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Metacam Drug Class

Metacam is part of the drug class:

Side Effects of Metacam

Serious side effects have been reported with meloxicam. See “Drug Precautions” section.

Common side effects of meloxicam include:

  • diarrhea
  • upper respiratory infection
  • upset stomach
  • flu-like symptoms
  • edema, or swelling
  • stomach pain
  • gas
  • digestive problems
  • heartburn
  • nausea
  • headache
  • dizziness

This is not a complete list of meloxicam side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Metacam Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • ACE inhibitors such as lisinopril (Prinivil), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec) and others
  • aspirin (Ecotrin) and other non-steroidal anti-inflammatory drugs (NSAIDs)
  • diuretics, or water pills, such as thiazides (hydrochlorothiazide) and furosemide (Lasix)
  • lithium (Eskalith, Lithobid, others)
  • methotrexate (Rheumatrex, Trexall)
  • cyclosporine (Neoral, Gengraf, Sandimmune)
  • warfarin (Coumadin)
  • cholestyramine (Questran)
  • cimetidine (Tagamet)
  • digoxin (Digitek, Lanoxin)

This is not a complete list of meloxicam drug interactions. Ask your doctor or pharmacist for more information.

Metacam Precautions

Serious side effects have been reported with meloxicam including:

  • Cardiovascular thrombotic events. Meloxicam can increase your risk of cardiovascular and heart diseases such as strokes and myocardial infarctions, which can lead to death. Tell your doctor if you have a history of heart disease.
  • Gastrointestinal effects. Meloxicam can cause digestive tract problems such as ulcers, bleeding, inflammation, and perforations (small holes). Tell your doctor if you have a history of digestive problems, or if you smoke or frequently drink alcohol. Alert your doctor if you take anticoagulants (blood-thinners) or corticosteroids such as prednisone.
  • Hepatic events. Meloxicam c­­an cause damage to the liver and increase liver tests. Tell your doctor if you have a history of liver disease.
  • Hypertension. Meloxicam may raise your blood pressure. Tell your doctor if you have a history of high blood pressure or take ACE inhibitors (such as lisinopril and enalapril) or diuretics (water pills).
  • Congestive heart failure and edema. Meloxicam can increase the chance of congestive heart failure, fluid retention, and weight gain.
  • Renal effects. Kidney damage can result from the use of meloxicam. Tell your doctor if you have a history of kidney disease or take ACE inhibitors (such as lisinopril and enalapril) or diuretics (water pills).
  • Hypersensitivity reaction. An allergic reaction to meloxicam can occur. Symptoms of a hypersensitivity reaction include:
    • hives
    • rash
    • difficulty breathing or swallowing
    • itching
    • swelling
  • Adverse skin reactions. Meloxicam can lead to dangerous skin reactions. Symptoms of a skin reaction include:
    • rash
    • red, itchy, or scaly skin
    • blisters
    • fever
  • Pregnancy. Meloxicam should not be taken past the 30th week of pregnancy.

Meloxicam can cause dizziness. Do not drive or operate heavy machinery until you know how meloxicam affects you.

Do not take meloxicam if you:

  • are allergic to meloxicam (Mobic)
  • will have or have recently had coronary (heart) surgery

Metacam Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of meloxicam, there are no specific foods that you must exclude from your diet when receiving meloxicam.

 

Inform MD

Before taking meloxicam tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • have a history of heart, liver, or kidney disease
  • have a history of gastrointestinal (digestive) problems
  • have hypertension, or high blood pressure
  • have a history of asthma
  • take ACE inhibitors such as lisinopril (Prinivil) and enalapril (Vasotec)
  • take aspirin (Ecotrin) and other non-steroidal anti-inflammatory drugs (NSAIDs)
  • take diuretics, or water pills, such as thiazides (hydrochlorothiazide) and furosemide (Lasix)
  • are allergic to meloxicam (Mobic)
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Metacam and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Meloxicam falls into category C before the 30th week of pregnancy, and category D after the 30th week.

For Pregnancy Category C before the 30th week of pregnancy: Studies in animals have shown a harmful and undesired effect on the unborn baby, yet there are no adequate and well-controlled studies in pregnant women. This medication may be given to a pregnant woman if her healthcare provider believes that its benefits to the pregnant woman outweigh any possible risks to her unborn baby.

For Pregnancy Category D after the thirtieth week of pregnancy: Meloxicam should be avoided during the third trimester of pregnancy. There is evidence of risk to the unborn baby based on studies in humans or adverse reaction data. 

Metacam and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if meloxicam is excreted in human breast milk or if it will harm your nursing baby.

Metacam Usage

  • Take meloxicam exactly as prescribed.
  • This medication comes in tablet and oral suspensions forms and is taken once a day, with or without food.
  • The oral suspension of meloxicam should be shaken before use.
  • If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of meloxicam at the same time.

Metacam Dosage

Take meloxicam exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

Your doctor will prescribe the appropriate dose of meloxicam depending on the severity of your arthritis and your response to the medication. The dosage range of meloxicam is between 7.5 and 15 mg per day for adults. The maximum daily dose of meloxicam is 15 mg for adults.

For the treatment of children over two years old with juvenile rheumatoid arthritis, the child’s body weight will determine the dosage of the medication. The maximum daily dose in children is 7.5 mg.

Metacam Overdose

If you take too much meloxicam, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

 

Other Requirements

  • Store meloxicam at room temperature.
  • Keep this medication in a dry place.
  • Keep this and all medicines out of the reach of children.

Metacam FDA Warning

Cardiovascular Risk:

NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may increase with duration of use. Patients with cardiovascular disease or risk factors for cardiovascular disease may be at greater risk.

Meloxicam is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery.

Gastrointestinal Risk:

NSAIDs cause an increased risk of serious gastrointestinal adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients are at greater risk for serious gastrointestinal events.