Mekinist treats a certain type of skin cancer. Take Mekinist 1 hour before or 2 hours after a meal.
Mekinist is a prescription medication used to treat a certain type of melanoma (a type of skin cancer) that cannot be treated with surgery or that has spread to other parts of the body. Mekinist belongs to a group of drugs called kinase inhibitors. These work by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
Mekinist comes as a tablet to take by mouth. It is usually taken once a day on an empty stomach, at least 1 hour before or 2 hours after a meal. Take Mekinist at around the same time every day.
Common side effects include rash, diarrhea, and swelling of the face, arms, or legs.
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Uses of Mekinist
Mekinist is a prescription medication used to treat a certain type of melanoma (a type of skin cancer) that cannot be treated with surgery or that has spread to other parts of the body.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Side Effects of Mekinist
Common side effects of Mekinist include:
- swelling of the face, arms, or legs
This is not a complete list of this medication’s side effects. Ask your doctor or pharmacist for more information.
Tell your doctor if you have any side effect that bothers you or that does not go away.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
No drug interactions have been studied. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.
Mekinist may cause serious side effects, including:
- heart problems, including heart failure. Your healthcare provider should check your heart function before you start taking Mekinist and during treatment. Signs and symptoms of heart problems may include:
- feeling like your heart is pounding or racing
- shortness of breath
- swelling of your ankles and feet
- feeling lightheaded
- eye problems. Mekinist can cause eye problems including blindness. Tell your healthcare provider right away if you get these symptoms of eye problems:
- blurred vision, loss of vision, or other vision changes
- see color dots
- halo (seeing blurred outline around objects)
- lung or breathing problems. Tell your healthcare provider if you have any new or worsening symptoms of lung or breathing problems, including:
- shortness of breath
- skin rash. Rash is the most common side effect of Mekinist and in some cases can be severe and can result in admission to the hospital if severe. Tell your healthcare provider if you get any of the following symptoms:
- skin rash
- redness, swelling, peeling, or tenderness of hands or feet
- skin redness
Do not take Mekinist if you are allergic to it or to any of its inactive ingredients.
Mekinist Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of this medication, there are no specific foods that you must exclude from your diet.
Before you take Mekinist, tell your healthcare provider if you:
- have heart problems
- have lung or breathing problems
- have eye problems
- have high blood pressure (hypertension)
- have liver or kidney problems
- have any other medical conditions
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
Mekinist and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.
This medication falls into category D. Mekinist can harm your unborn baby. Women who may become pregnant should use effective birth control (contraception) during treatment with Mekinist and for 4 months after stopping treatment. Talk to your healthcare provider about birth control methods that may be right for you. Tell your healthcare provider right away if you become pregnant during treatment with Mekinist.
Mekinist and Lactation
It is not known if Mekinist passes into your breast milk. You and your healthcare provider should decide if you will take Mekinist or breastfeed. You should not do both.
- Take Mekinist exactly as your healthcare provider tells you to take it. Do not change your dose or stop Mekinist unless your healthcare provider tells you.
- Take Mekinist one time a day.
- Take Mekinist 1 hour before or 2 hours after meals.
- If you miss a dose, take it as soon as you remember. If it is within 12 hours of your next scheduled dose, skip the missed dose. Just take the next dose at your regular time.
Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. The dose your doctor recommends may be based on the following:
- the condition being treated
- other medical conditions you have
- other medications you are taking
- how you respond to this medication
- your weight
- your height
- your age
- your gender
The recommended dose is 2 mg by mouth once daily. Take at least 1 hour before or 2 hours after a meal. Do not take a missed dose within 12 hours of the next dose.
If you take too much this medication, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.
If this medication is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
- Store Mekinist in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze.
- Keep Mekinist dry and away from moisture.
- The bottle of Mekinist contains a desiccant packet to help keep your medicine dry. Do not throw away the desiccant packet.
- Keep Mekinist in its original bottle. Do not place tablets in a pill box.
- Safely throw away Mekinist that is out of date or no longer needed.
- Keep Mekinist and all medicine out of the reach of children.