Lysteda treats women with heavy monthly periods. Don't take Lysteda until your period has started and don't take for more than 5 days in a row.

Lysteda Overview


Lysteda is a prescription medicine used to treat women with heavy monthly periods (menstruation) that get in the way of social, leisure, and physical activities. Lysteda belongs to a group of drugs called antifibrinolytics. These work to to improve blood clotting.

This medication comes in tablet form and is usually taken 3 times a day for a maximum of 5 days during the monthly period.
Common side effects of Lysteda include headache, back pain, fatigue, nausea, vomiting, and diarrhea.


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  • Blood Coagulation Disorders
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Lysteda Cautionary Labels


Uses of Lysteda

Lysteda is a prescription medicine used to treat adult women with heavy monthly periods (menstruation) when bleeding gets in the way of social, leisure and physical activities. 

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


Side Effects of Lysteda

Lysteda can cause serious side effects, including:

  • Blood clots. The risk of serious blood clots may be increased when Lysteda is taken with:
    • hormonal contraceptives, especially if you are taking higher than your normal dose of birth control, are overweight, or if you smoke cigarettes
    • medicines used to help your blood clot
    • some medicines used to treat leukemia
  • Eye changes. Stop taking Lysteda and promptly report any eye problems you have while taking Lysteda. Your doctor will refer you to an eye doctor who will examine your eyes.
  • Allergic reaction. If you have severe shortness of breath and your throat feels tight, stop taking Lysteda and get medical care right away.

The most common side effects of Lysteda include:

  • Headaches
  • Sinus and nasal problems
  • Back pain
  • Pain in your abdomen
  • Pain in your muscles or joints
  • Anemia
  • Fatigue

Tell your healthcare provider if you have any side effect that bothers you or does not go away.

These are not all of the possible side effects of Lysteda. For more information, ask your healthcare provider or pharmacist.

If you notice a change in your usual bleeding pattern that worries you, or your heavy bleeding continues, contact your healthcare provider right away. This may be a sign of a more serious condition.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects to Ferring Pharmaceuticals Inc. at 1-888-FERRING (1-888-337-7464).

Lysteda Interactions

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Lysteda and other medicines can affect each other, causing side effects. Lysteda can affect the way other medicines work and other medicines can affect how Lysteda works.

Especially tell your healthcare provider if you take:

  • Birth control pills or other hormonal birth control
  • Medicines used to help your blood clot
  • Medicines used to break up blood clots
  • Any medicines to treat leukemia

Ask your healthcare provider if you are not sure if your medicine is one that is described above.

Lysteda Precautions

Do not take Lysteda if you:

  • Currently have a blood clot
  • Have ever had a blood clot
  • Have been told that you are at risk of having a blood clot
  • Are taking combination hormonal contraceptive medication
  • Are allergic to Lysteda

Lysteda Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Lysteda there are no specific foods that you must exclude from your diet when receiving Lysteda.


Inform MD

Before taking Lysteda, tell your healthcare provider about all of your medical conditions, including whether:

  • You have ever had a blood clot or been told that you are at risk of having a blood clot
  • You are using a form of birth control that contains hormones (like a birth control pill, patch, vaginal ring or intrauterine device). Also tell your healthcare provider if you are taking higher than your normally-prescribed dose of birth control. Using hormonal products along with Lysteda, especially if you are overweight or smoke, may increase your chance of having a serious blood clot, stroke, or heart attack.
  • You have acquired defective color vision
  • You have a subarachnoid hemorrhage
  • You are pregnant or think you may be pregnant
  • You are breastfeeding or plan to breastfeed. Lysteda can pass into your milk. Talk to your healthcare provider about the best way to feed your baby if you take Lysteda.
  • The time between the start of your periods is less than 21 days or more than 35 days
  • You have any other medical conditions

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Lysteda and Pregnancy

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Lysteda falls into category B. There are no well-done studies that have been done in humans with Lysteda. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication.


Lysteda and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Lysteda has been detected in human breast milk. Because of the possibility for adverse reactions in nursing infants from Lysteda, a choice should be made whether to stop nursing or to stop use of this medication. The importance of the drug to the mother should be considered.


Lysteda Usage

Take Lysteda exactly as your healthcare provider tells you.

  • Do not take Lysteda until your period has started.
  • Do not take Lysteda for more than 5 days in a row.
  • Do not take Lysteda when you do not have your period.
  • Once your period has started, take 2 tablets of Lysteda three times per day (e.g., in the morning, afternoon, and evening).
  • Lysteda tablets should be swallowed whole and not chewed or broken apart.
  • Lysteda may be taken with or without food.
  • Do not take more than 6 tablets of Lysteda in a day. If you take more than 6 tablets, call your healthcare provider.
  • If you miss a dose, take it when you remember, and then take your next dose at least six hours later. Do not take more than two tablets at a time to make up for missed doses.
  • If Lysteda does not help to lessen bleeding with your periods after 2 cycles or seems to stop working, talk to your healthcare provider.

Lysteda Dosage

The recommended dose of Lysteda is two 650 mg tablets taken three times daily for up to 5 days during monthly menstruation. If you have kidney disease, the daily Lysteda dose may be lowered.

Lysteda Overdose

If you take too much Lysteda, call your local Poison Control Center or seek emergency medical attention right away.

Other Requirements

  • Store Lysteda at room temperature between 59°F to 86°F (15°C to 30°C).
  • Keep Lysteda and all medicines out of the reach of children.