Lithobid

Lithobid helps treat and prevent episodes of mania in people with bipolar disorder.

Lithobid Overview

Reviewed: November 10, 2014
Updated: 

Lithobid is a prescription medication used to treat and prevent episodes of mania in people with bipolar disorder (also known as manic-depressive disorder), a disorder that causes episodes of depression, mania, and other abnormal moods. Lithobid belongs to a group of medications called antimanic agents. It works by decreasing abnormal activity in the brain.

Lithobid is available as an extended-release (long-acting) tablet to take by mouth. It is usually taken 2 or 3 times a day. Do not chew, crush, or divide extended-release lithium tablets. Swallow tablets whole.

Common side effects of Lithobid include uncontrollable shaking in the hands, increased urination, thirst, and nausea.

Lithobid can also cause dizziness, drowsiness, and blurred vision. Do not drive or operate heavy machinery until you know how Lithobid affects you.

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Lithobid Cautionary Labels

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Uses of Lithobid

Lithobid is a prescription medication used to treat and prevent episodes of mania in people with bipolar disorder (also known as manic-depressive disorder), a disorder that causes episodes of depression, mania, and other abnormal moods. Lithobid belongs to a group of medications called antimanic agents. It works by decreasing abnormal activity in the brain.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Lithobid Drug Class

Lithobid is part of the drug class:

Side Effects of Lithobid

Serious side effects have been reported with Lithobid. See the "Lithobid Precautions" section.

Common side effects of lithium include:

  • fine hand tremor
  • increased urination
  • thirst
  • nausea

This is not a complete list of Lithobid side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Lithobid Interactions

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • acetazolamide (Diamox)
  • aminophylline
  • angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril, lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik)
  • angiotensin II receptor antagonists such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan)
  • antacids such as sodium bicarbonate
  • caffeine (found in certain medications to treat drowsiness and headaches)
  • calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac, others), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nymalize), nisoldipine (Sular), and verapamil (Calan, Covera, Verelan)
  • carbamazepine (Tegretol)
  • medications for mental illness such as haloperidol (Haldol)
  • methyldopa (Aldomet)
  • metronidazole (Flagyl)
  • nonsteroidal anti-inflammatory drugs (NSAIDs) such as celecoxib (Celebrex), indomethacin (Indocin), and piroxicam (Feldene)
  • potassium iodide
  • selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft)
  • theophylline (Theolair, Theochron)

This is not a complete list of Lithobid drug interactions. Ask your doctor or pharmacist for more information.

Lithobid Precautions

Serious side effects have been reported with Lithobid, including:

  • Lithium toxicity. Tell your healthcare provider right away if you have some or all of the following symptoms of lithium toxicity:
    • diarrhea
    • vomiting
    • drowsiness
    • muscular weakness
    • lack of coordination
    • giddiness
    • blurred vision
    • ringing in the ears
    • increased volume of urination
  • Neuromuscular side effects. Tell your healthcare provider right away if you have some or all of the following symptoms of neuromuscular side effects:
    • ​tremor
    • muscle twitching
  • ​Central nervous system side effects. Tell your healthcare provider right away if you have some or all of the following symptoms of central nervous system side effects:
    • ​seizures
    • slurred speech
    • dizziness
    • vertigo
    • incontinence of urine or feces
    • sleepiness
    • restlessness
    • confusion
  • ​Cardiovascular side effects. Tell your healthcare provider right away if you have some or all of the following symptoms of cardiovascular side effects:
    • ​irregular heartbeat
    • low blood pressure
  • ​Gastrointestinal side effects. Tell your healthcare provider right away if you have some or all of the following symptoms of gastrointestinal side effects:
    • ​decreased appetite
    • vomiting
    • nausea
    • diarrhea
  • ​Dermatologic side effects. Tell your healthcare provider right away if you have some or all of the following symptoms of dermatologic side effects:
    • drying and ​thinning of the hair
    • exacerbation of psoriasis
    • loss of feeling in the skin
    • infections of the skin

Lithobid can also cause dizziness, drowsiness, and blurred vision. Do not drive or operate heavy machinery until you know how Lithobid affects you.

Do not take Lithobid if you:

  • are allergic to lithium or to any of its ingredients
  • have kidney disease
  • have cardiovascular disease
  • are dehydrated
  • are taking diuretics

Lithobid Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Lithobid, there are no specific foods that you must exclude from your diet when receiving this medication.

However, it is important to follow a proper diet while taking Lithobid. This includes adequate amounts of salt and liquids in your diet. Ask your doctor about the diet that is right for you. Also talk to your doctor about drinking drinks that contain caffeine while taking Lithobid.

Inform MD

Before taking Lithobid, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to lithium or to any of its ingredients
  • have kidney disease
  • have cardiovascular disease
  • have organc brain syndrome
  • have thyroid disease
  • have fainted without explanation
  • have a family history of Brugada syndrome or if anyone in your family died suddenly with no explanatin before the age of 45

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Lithobid and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X - are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Lithobid falls into category D. It has been shown that the use of lithium in pregnant women caused some babies to be born with problems. However, in some serious situations, the benefit of using this medication may be greater than the risk fo harm to the baby.

Lithobid and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Lithobid has been detected in human breast milk. Lithium should not be used by nursing mothers, except in rare and unusual circumstances in which, in the view of the physician, the potential benefits to the mother outweigh possible hazards to the child.

Lithobid Usage

Take Lithobid exactly as prescribed.

Lithobid is also available as an extended-release (long-acting) tablet to take by mouth. It is usually taken 2 or 3 times a day. Do not chew, crush, or divide extended-release Lithobid tablets. Swallow tablets whole.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take 2 doses of Lithobid at the same time.

Lithobid Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • how you respond to this medication

The recommended dose of Lithobid for acute episodes of mania is 900 mg 2 times a day.

The recommended dose of Lithobid for long-term control and prevention of episodes of mania is 600 mg 2 or 3 times a day.

Doses of Lithobid should be individualized on the basis of response to therapy and levels of lithium in your blood.

Lithobid Overdose

If you take too much Lithobid, call your healthcare provider or local Poison Control Center or seek emergency medical attention right away.

If Lithobid is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store Lithobid at room temperature.
  • Protect this medication from moisture.
  • Keep this and all medications out of the reach of children.

Lithobid FDA Warning

Warning

Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. Facilities for prompt and accurate serum lithium determinations should be available before initiating therapy.