Latuda treats schizophrenia and bipolar depression. To ensure this medication works the best, take this medication with food (meal should be at least 350 calories).

Now Playing
Pharmacist Amanda Pena, PharmD overviews the uses and common side effects of Latuda.
Atypical antipsyc...
Next Video
Atypical antipsyc...
Pharmacist Amanda Pena, PharmD overviews the uses and common side effects of Latuda.
Atypical antipsychotics
Atypical antipsychotics
Pharmacist Trey Robinson, PharmD summarizes the uses, common side effects, and warnings for the Atypical antipsychotics class of medications

Latuda Overview


Latuda is a prescription medication used to treat schizophrenia and bipolar depression. Latuda belongs to a group of drugs called atypical antipsychotics. These medications work by acting on certain receptors in the brain that affect mood and behavior.

This medication comes in tablet form and is usually taken once daily, with food.

Common side effects include restlessness, nausea, and drowsiness. Do not drive or operate heavy machinery until you know how this medication affects you.


Patient Ratings for Latuda

How was your experience with Latuda?

First, a little about yourself

Tell us about yourself in a few words?

What tips would you provide a friend before taking Latuda?

What are you taking Latuda for?

Choose one
  • Other
  • Schizophrenia And Disorders With Psychotic Features

How long have you been taking it?

Choose one
  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did Latuda work for you?

Did you experience many side effects while taking this drug?

How likely would you be to recommend Latuda to a friend?

Pill Images

{{ }}
pill-image {{ }}
Color: {{ slide.color }} Shape: {{ slide.shape }} Size: {{ slide.size }} Score: {{ slide.score }} Imprint: {{ slide.imprint }}
{{ slide.number }} of {{ }}

Latuda Cautionary Labels


Uses of Latuda

Latuda is a prescription medication used to treat schizophrenia and depression associated with bipolar I disorder.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


Latuda Drug Class

Latuda is part of the drug class:

Side Effects of Latuda

Serious side effects have been reported with Latuda. See "Drug Precautions" section.

Common side effects include:

  • sleepiness or drowsiness
  • restlessness and feeling like you need to move around (akathisia)
  • difficulty moving, slow movements, muscle stiffness, or tremor
  • nausea

These are not all the possible side effects of Latuda. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Latuda Interactions

Tell your doctor about all the medicines you take including prescription and nonprescription medications, vitamins, and herbal supplements. Especially tell your doctor if you take medicines for:

  • depression
  • high blood pressure - such as diltiazem (Cardizem, Cartia, Taztia, Tiazac, others), and verapamil (Calan, Covera, Isoptin, Verelan, in Tarka, and others)
  • Parkinson's disease
  • trouble sleeping
  • abnormal heart beats or rhythm
  • epilepsy - such as carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital, and phenytoin (Dilantin, Phenytek)
  • inflammation
  • psychosis

This is not a complete list of Latuda drug interactions. Ask your doctor or pharmacist for more information.

Latuda Precautions

Serious side effects have been reported including:

  1. Increased risk of death in elderly people who are confused, have memory loss and have lost touch with reality (dementia-related psychosis). Medicines like Latuda can increase the risk of death in elderly people who are confused, have memory loss and have lost touch with reality (dementia-related psychosis). Latuda should not be used to treat people with dementia-related psychosis.
  2. Increased risk of suicidal thoughts or actions (antidepressant medicines, depression and other serious mental illnesses, and suicidal thoughts or actions).
    • Talk to your, or your family member's, healthcare provider about:
      • all risks and benefits of treatment with antidepressant medicines.
      • all treatment choices for depression or other serious mental illness.
    • Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults within the first few months of treatment.
    • Depression and other serious mental illnesses are the most important causes of suicidal thoughts and actions. Some people may have a particularly high risk of having suicidal thoughts or actions. These include people who have (or have a family history of) depression, bipolar illness (also called manic-depressive illness), or a history of suicidal thoughts or actions.
    • How can I watch for and try to prevent suicidal thoughts and actions in myself or a family member?
      • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.
      • Call the healthcare provider right away to report new or sudden changes in mood, behavior, thoughts, or feelings.
      • Keep all follow-up visits with the healthcare provider as scheduled. Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.

Call a healthcare provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you:

  • thoughts about suicide or dying
  • attempts to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling very agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, being angry, or violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

Do not take Latuda if you:

  • are allergic to Latuda hydrochloride or any of the other ingredients in Latuda.
  • are taking certain other medicines called CYP3A4 inhibitors or inducers including ketoconazole, clarithromycin, ritonavir, voriconazole, mibefradil, rifampin, avasimibe, St. John's wort, phenytoin, or carbamazepine. Ask your healthcare provider if you are not sure if you are taking any of these medicines.

Latuda Food Interactions

Grapefruit and grapefruit juice may interact with Latuda and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.



Inform MD

Before you take Latuda, tell your healthcare provider if you:

  • have or have had diabetes or high blood sugar in you or your family. Your healthcare provider should check your blood sugar before you start Latuda and also during therapy.
  • have or have had high levels of total cholesterol, triglycerides or LDL-cholesterol or low levels of HDL-cholesterol
  • have or have had low or high blood pressure
  • have or have had low white blood cell count
  • have or have had seizures
  • have or have had abnormal thyroid tests
  • have or have had high prolactin levels
  • have or have had heart problems
  • have or have had liver problems
  • have or have had any other medical conditions
  • are pregnant or breastfeeding

Tell the healthcare provider about all the medicines that you take or recently have taken including prescription medicines, over-the-counter medicines, herbal supplements and vitamins.

Latuda and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Latuda falls into category B. It is not known if Latuda will harm your unborn baby. This medication should be used during pregnancy only if the potential benefit to the mother justifies the risk to the unborn baby.

Latuda and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Latuda crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Latuda.


Latuda Usage

  • Take Latuda exactly as your healthcare provider tells you to take it. Do not change the dose yourself.
  • Take Latuda by mouth, with food (at least 350 calories).
  • If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of Latuda at the same time.

While taking Latuda, avoid the following:

  • Avoid eating grapefruit or drinking grapefruit juice while you take Latuda since these can affect the amount of Latuda in the blood.
  • Do not drive, operate machinery, or do other dangerous activities until you know how Latuda affects you. Latuda may make you drowsy.
  • Avoid getting overheated or dehydrated.
  • Do not over-exercise.
  • In hot weather, stay inside in a cool place if possible.
  • Stay out of the sun. Do not wear too much or heavy clothing.
  • Drink plenty of water.
  • Do not drink alcohol while taking Latuda. It may make some side effects of Latuda worse.

Latuda Dosage

Take Latuda exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The Latuda dose your doctor recommends will be based on the following: 

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication

The recommended starting dose is 20 mg for depression associated with bipolar disease and 40 mg for schizophrenia. The maximum recommended maintenance dose is 160 mg.

Latuda Overdose

If you take too much Latuda, call your healthcare provider or poison control center at 1-800-222-1222 right away, or go to the nearest hospital emergency room.

Other Requirements

  • Store Latuda tablets at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep Latuda and all medicines out of the reach of children.

Latuda FDA Warning


  • Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death.
  • Latuda is not approved for use in patients with dementia-related psychosis.
  • Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; there was a reduction in risk with antidepressant use in patients aged 65 and older.
  • In patients of all ages who are started on antidepressant therapy, monitor closely for worsening, and for emergence of suicidal thoughts and behaviors. Advise families and caregivers of the need for close observation and communication with the prescriber.