Hydroxyzine relieves itching caused by allergies, controls nausea and vomiting caused by various conditions, and treats anxiety. Hydroxyzine can cause drowsiness and dry mouth.

Hyzine Overview


Hydroxyzine is a prescription medication used to control nausea and vomiting, to relieve itching caused by allergic conditions, and to cause sedation before and after general anesthesia and in the treatment of psychiatric disorders.

Hydroxyzine belongs to a group of drugs called antihistamines. It works by blocking histamine and acetylcholine receptors in the body, and by suppressing activity in the brain.

This medication comes in tablet, capsule, syrup, and intramuscular injectable forms. It is taken up to 4 times daily, with or without food.

Common side effects include dry mouth, nausea, and drowsiness. Do not drive or operate heavy machinery until you know how it affects you.

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  • Other
  • Anxiety Disorders
  • Nausea
  • Pruritus
  • Substance Withdrawal Syndrome
  • Vomiting

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Uses of Hyzine

Hydroxyzine is a prescription medication used:

  • for sedation to relieve anxiety, agitation, and tension caused by certain psychiatric disorders
  • for sedation before and after general anesthesia
  • to reduce itching caused by allergic conditions or certain pain medications
  • to control nausea and vomiting

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.



For more information on this medication choose from the list of selections below.

Hyzine Drug Class

Hyzine is part of the drug class:

Side Effects of Hyzine

Common side effects include:

  • dry mouth
  • drowsiness
  • nausea
  • dizziness

This is not a complete list of hydroxyzine side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.