 is a prescription medication used to treat high blood pressure and to lower the chance of stroke in people with heart disease. Hyzaar is a single tablet containing 2 prescription drugs. Losartan belongs to a group of drugs called angiotensin II receptor blockers (ARBs), which help blood vessels to relax. Hydrochlorothiazide belongs to a group of drugs called diuretics ( "Pin It")
Hyzaar Overview
Hyzaar (generic: losartan/hydrochlorothiazide) is a prescription medication used to treat high blood pressure and to lower the chance of stroke in people with heart disease. Hyzaar is a single tablet containing 2 prescription drugs. Losartan belongs to a group of drugs called angiotensin II receptor blockers (ARBs), which help blood vessels to relax. Hydrochlorothiazide belongs to a group of drugs called diuretics ("water pills"), which help the body get rid of excess fluid.
This medication comes in tablet form and is taken once a day, with or without food.
Common side effects of Hyzaar include colds, dizziness, stuffy nose, and back pain.
Uses of Hyzaar
Hyzaar is a prescription medicine used in adults to treat high blood pressure and lower the chance of stroke in patients with high blood pressure and a heart problem called left ventricular hypertrophy.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Side Effects of Hyzaar
Hyzaar may cause the following side effects that may be serious:
- injury or death of unborn babies (see"Drug Precautions").
- allergic reaction. Symptoms of an allergic reaction are swelling of the face, lips, throat, or tongue. Get emergency medical help right away and stop taking Hyzaar.
- low blood pressure (hypotension). Low blood pressure may cause you to feel faint or dizzy. Lie down if you feel faint or dizzy. Call your doctor right away.
- a new or worsening condition called systemic lupus erythematosus (Lupus; SLE)
- if you have kidney problems, you may see a worsening in how well your kidneys work. Call your doctor if you get swelling in your feet, ankles, or hands, or unexplained weight gain.
- If you have liver problems, you may see a worsening in how well your liver works. Call your doctor if you get nausea, pain in the right upper stomach area (abdomen), yellow eyes or skin (which can be itchy).
The most common side effects of Hyzaar in people with high blood pressure are:
- "colds" (upper respiratory infection)
- dizziness
- stuffy nose
- back pain
- fast or irregular heartbeat (palpitations)
- rash
Tell your doctor if you get any side effect that bothers you or that won't go away.
Hyzaar Interactions
Tell your doctor about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Hyzaar and certain other medicines may interact with each other.
Especially tell your doctor if you are taking:
- potassium supplements
- salt substitutes containing potassium
- water pills (diuretics)
- lithium (a medicine used to treat a certain kind of depression)
- medicines used to treat pain and arthritis, called non-steroidal anti-inflammatory drugs (NSAIDs), including COX-2 inhibitors.
Hyzaar Precautions
Do not take Hyzaar if you:
- are allergic to any ingredients in Hyzaar.
- are allergic to any sulfonamide-containing ("sulfa") medicines. Ask your doctor if you are not sure what sulfonamide-containing ("sulfa") medicines are.
- are not passing urine.
Do not take Hyzaar if you are pregnant or plan to become pregnant. Hyzaar can harm your unborn baby causing injury and even death. Stop taking Hyzaar if you become pregnant and call your doctor right away. If you plan to become pregnant, talk to your doctor about other treatment options before taking Hyzaar.
Hyzaar Food Interactions
Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Hyzaar there are no specific foods that you must exclude from your diet when receiving Hyzaar.
Inform MD
Tell your doctor about all your medical conditions including if you:
- are pregnant or planning to become pregnant.
- are breastfeeding or plan to breastfeed. Hyzaar can pass into your milk and may harm your baby. You and your doctor should decide if you will take Hyzaar or breastfeed. You should not do both.
- have been vomiting (throwing up), having diarrhea, sweating a lot, or not drinking enough fluids. These could cause you to have low blood pressure.
- have liver problems
- have kidney problems
- have systemic lupus erythematosus (Lupus; SLE)
- have diabetes
- have asthma
- have gout
- have any allergies
Tell your doctor about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Hyzaar and certain other medicines may interact with each other.
Especially tell your doctor if you are taking:
- potassium supplements
- salt substitutes containing potassium
- water pills (diuretics)
- lithium (a medicine used to treat a certain kind of depression)
- medicines used to treat pain and arthritis, called non-steroidal anti-inflammatory drugs (NSAIDs), including COX-2 inhibitors.
Hyzaar and Pregnancy
Tell your doctor if you are pregnant or planning to become pregnant. Hyzaar can cause harm or even death to your unborn baby.
Hyzaar and Lactation
Tell your doctor if you are breastfeeding or planning to breastfeed. It is not known if Hyzaar is excreted in human breast milk or if it will harm your nursing baby.
Hyzaar Usage
Take Hyzaar exactly as prescribed by your doctor. Your doctor may change your dose if needed. Hyzaar can be taken with or without food. If you miss a dose, take it as soon as you remember. If it is close to your next dose, do not take the missed dose. Just take the next dose at your regular time. If you take too much Hyzaar, call your doctor or Poison Control Center, or go to the nearest hospital emergency room right away. Your doctor may do blood tests from time to time while you are taking Hyzaar.
Hyzaar Dosage
Take Hyzaar exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. Your doctor will determine the best dose for you. Do not adjust the dose unless your doctor tells you to do so.
The recommended dosage of Hyzaar for people with high blood pressure (hypertension) will vary between Hyzaar 50 mg/12.5 mg and Hyzaar 100 mg/25 mg once a day. Depending upon blood pressure response, the dose may be increased or decreased. It may take up to a month for the full blood pressure lowering effect of Hyzaar to be seen.
Hyzaar Overdose
If you take too much Hyzaar, call your doctor or Poison Control Center, or go to the nearest hospital emergency room right away.
Forms of Hyzaar
Hyzaar tablets are available in the following strengths: 50-12.5 mg, 100-12.5 mg, 100-25 mg.
The active ingredients in Hyzaar are losartan potassium and hydrochlorothiazide.
Inactive ingredients: microcrystalline cellulose, lactose hydrous, pregelatinized starch, magnesium stearate, hydroxypropyl cellulose, hypromellose, titanium dioxide. Hyzaar 50-12.5 and Hyzaar 100-25 also contain D&C yellow No. 10 aluminum lake. Hyzaar 50-12.5, Hyzaar 100-12.5, and Hyzaar 100-25 may also contain carnauba wax.
Other Requirements
- Store Hyzaar at room temperature at 59°F to 86°F (15°C to 30°C).
- Keep Hyzaar in a tightly closed container, and keep Hyzaar out of the light.
- Keep Hyzaar and all medicines out of the reach of children.
Hyzaar FDA Warning
USE IN PREGNANCY
When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, Hyzaar should be discontinued as soon as possible.
