Donepezil and Memantine

Donepezil/memantine treats dementia in people with Alzheimer's disease.

Donepezil and Memantine Overview


Donepezil/memantine is a prescription medication used to treat dementia in people with Alzheimer's disease. It is a combination medication comprised of a NMDA receptor antagonist (memantine), and an acetylcholinesterase inhibitor (donepezil).

Donepezil/memantine improves mental function by decreasing abnormal activity in the brain and by increasing the amount of a certain naturally occurring substance in the brain.

Donepezil/memantine comes as a capsule to be taken by mouth, once daily. The capsules can be opened to allow the contents to be sprinkled on food for patients who have difficulty swallowing.

Common side effects include headache, diarrhea and dizziness.

Patient Ratings for Donepezil & Memantine

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Uses of Donepezil and Memantine

Donepezil/memantine is a prescription medication approved for the treatment of moderate to severe dementia of the Alzheimer's type in patients stabilized on memantine and donepezil.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Donepezil and Memantine Brand Names

Donepezil and Memantine may be found in some form under the following brand names:

Donepezil and Memantine Drug Class

Donepezil and Memantine is part of the drug class: