Differin treats acne. Can make your skin more sensitive to sunlight and may cause you to sunburn more easily. Avoid sunlight. If you are going to be outside, wear sunscreen and protective clothing.

Differin Overview

Reviewed: August 20, 2013

Differin is a prescription medication used to treat acne. Differin, a form of vitamin A, is thought to work by reducing inflammation and slowing the growth of keratin surface skin cells. This helps to unblock pores and decreases the formation of blackheads and pimples.

This medication comes in the form of a cream, a gel, and a lotion to be applied to the affected skin. It is usually applied once daily, at nighttime, after gently washing with a mild cleanser.

Common side effects include skin irritation, redness, peeling, and dryness.

Patient Ratings for Differin

How was your experience with Differin?

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What are you taking Differin for?

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  • Other
  • Acne Vulgaris

How long have you been taking it?

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  • Less than a week
  • A couple weeks
  • A month or so
  • A few months
  • A year or so
  • Two years or more

How well did Differin work for you?

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Uses of Differin

Differin is a prescription medication used to treat acne.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.



For more information on this medication choose from the list of selections below.

Differin Drug Class

Differin is part of the drug class:

Side Effects of Differin

Serious side effects have been reported. See "Drug Precautions" section.

Common side effects include:

  • redness
  • scaling or peeling
  • dryness
  • persistent itching
  • persistent burning or stinging

This is not a complete list of Differin side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.