Depade treats alcohol dependence and opioid drug abuse. It will not be started unless there has not been ingestion of opiates for at least 7-10 days.

Depade Overview


Depade is a prescription medication used to treat alcohol dependence and opioid drug abuse. Depade belongs to a group of drugs called opiate antagonists. It works by reducing the craving for alcohol and blocking the effects of opiate medications and opioid street drugs.

This medication comes in tablet form and is taken once a day, with or without food.

Patient Ratings for Depade

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  • Other
  • Alcoholism

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Uses of Depade

Depade is a prescription medication used to treat alcohol dependence and opioid drug abuse.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.


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Depade Drug Class

Depade is part of the drug class:

Depade FDA Warning

Naltrexone has the capacity to cause hepatocellular injury when given in excessive doses.

Naltrexone is contraindicated in acute hepatitis or liver failure, and its use in patients with active liver disease must be carefully considered in light of its hepatotoxic effects.

The margin of separation between the apparently safe dose of naltrexone and the dose causing hepatic injury appears to be only five-fold or less. Naltrexone does not appear to be a hepatotoxin at the recommended doses.

Patients should be warned of the risk of hepatic injury and advised to stop the use of naltrexone and seek medical attention if they experience symptoms of acute hepatitis.