Delzicol

Delzicol treats an intestinal disease called ulcerative colitis. Stop taking this medication and call your doctor if you experience severe abdominal pain, bloody diarrhea, or develop a rash.

Delzicol Overview

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Delzicol is a prescription medication used to treat ulcerative colitis, or inflammation of the lining of the colon. It helps relieve the symptoms of ulcerative colitis including diarrhea, rectal bleeding, and stomach pain. Delzicol belongs to a group of drugs called aminosalicylates. These work by stopping the body from producing a certain substance that may cause pain or inflammation in the colon.

Delzicol comes in delayed-release capsules and are usually taken up to 3 times a day, 1 hour before or 2 hours after a meal. These should be swallowed whole, not chewed, crushed, or split.

Common side effects of Delzicol include stomach pain, pain, and rash. 

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Delzicol Cautionary Labels

precautions

Uses of Delzicol

Delzicol is a prescription medication used to treat ulcerative colitis (UC). UC is a condition in which part or all of the lining of the colon (also known as the large intestine) is swollen or worn away. It is used to keep it from coming back ("maintain remission").

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

 

 

Manufacturer

Delzicol Drug Class

Delzicol is part of the drug class:

Side Effects of Delzicol

Serious side effects have been reported with Delzicol. See “Delzicol Precautions” section.

Common side effects of Delzicol include:

  • stomach pain
  • pain
  • back pain
  • rash
  • indigestion
  • sneezing
  • runny nose
  • flu syndrome
  • gas
  • vomiting
  • fever
  • joint pain
  • constipation
  • gastrointestinal bleeding

This is not a complete list of Delzicol side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Delzicol Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • medicines that can damage the kidneys, including non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil) and aspirin (Ecotrin)
  • azathioprine (Imuran)
  • 6-mercaptopurine (Purinethol)
  • antacids such as Maalox, Mylanta, Mag-Ox, Caltrate, Tums, or Rolaids

This is not a complete list of Delzicol drug interactions.  Ask your doctor or pharmacist for more information.

 

Delzicol Precautions

Serious side effects have been reported with Delzicol including:

  • Kidney problems. Tell your doctor if you take non-steroidal anti-inflammatory drugs or have kidney disease. Your doctor will check your kidney function with a simple blood test before you start taking Delzicol.
  • Delzicol may worsen ulcerative colitis. Tell your doctor if you experience the following symptoms:
    • cramping
    • acute abdominal pain
    • bloody diarrhea
    • fever
    • headache
    • rash
  • Hypersensitivity reaction. An allergic reaction is possible with Delzicol. Tell your doctor if you are allergic to sulfasalazine (Azulfidine) or Delzicol. Serious reactions can lead to heart problems, like myocarditis or pericarditis.
  • Liver failure is possible with Delzicol. Tell your doctor if you have liver disease.
  • Upper GI tract obstruction. Pyloric stenosis or an obstruction in the digestive tract could prevent Delzicol from reaching the colon and treating ulcerative colitis.
  • Pericarditis (inflammation of the lining around the heart). Tell your doctor if you experience symptoms of pericarditis including chest pain, rapid heartbeat, difficulty breathing, and fever. Your doctor may want to temporarily stop use of Delzicol.

Intact, partially intact, and/or capsule shells have been reported in the stool. Contact your doctor if this occurs repeatedly.

Do not take Delzicol if you:

  • have kidney disease
  • are allergic to mesalamine or any ingredients in Delzicol
  • are allergic to salicylates (including aspirin)

Delzicol Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Delzicol, there are no specific foods that you must exclude from your diet when receiving this medication.

 

Inform MD

Before taking Delzicol, tell your doctor about all your medical conditions. Especially tell your doctor if you:

  • have had an allergic reaction to sulfasalazine (Azulfidine), salicylates (such as aspirin), or Delzicol
  • are taking nonsteroidal anti-inflammatory drugs such as ibuprofen (Advil) and aspirin (Ecotrin) or other drugs that affect the kidneys
  • are taking azathioprine (Imuran) or 6-mercaptopurine (Purinethol)
  • have cramping, abdominal pain, bloody diarrhea, fevers, headaches, or rashes
  • have a history of myocarditis or pericarditis
  • have had inflamed pancreas (pancreatitis)
  • are allergic to other things, such as foods, preservatives, or dyes
  • have kidney, liver, or heart disease
  • have a history of stomach blockage
  • repeatedly see intact, partially intact, and/or capsule shells in the stool
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescriptions medicines, vitamins, and herbal supplements.

Delzicol and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.  

The FDA categorizes medications based on safety for use during pregnancy. Five categories – A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Delzicol falls into category B. There are no well-controlled studies in pregnant women.

Delzicol and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed. The active ingredient in Delzicol is excreted in human breast milk. Caution should be taken when Delzicol is given to a nursing mother. 

Delzicol Usage

Take Delzicol exactly as prescribed. Do not change the dose or stop taking Delzicol without talking to your doctor.

Delzicol comes in delayed-release capsules and are usually taken up to 3 times a day, 1 hour before or 2 hours after a meal. These should be swallowed whole, not chewed, crushed, or split.

Delzicol Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

  • Delzicol (mesalamine delayed release capsules)
    • For the treatment of mildly to moderately active ulcerative colitis - 800 mg three times daily
    • For the maintenance of remission of ulcerative colitis - 1.6 g daily, in divided doses

Delzicol Overdose

If you take too much this medication, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

 

Other Requirements

  • Store Delzicol at room temperature.
  • Keep this and all medicines out of the reach of children.