Bromfenac

Bromfenac reduces inflammation and pain in patients who have undergone cataract surgery. Remove contact lenses before administering drops.

Bromfenac Overview

Reviewed: April 8, 2013
Updated: 

Bromfenac is a prescription medication used to treat eye inflammation and eye pain in patients who have undergone cataract surgery. Bromfenac belongs to a group of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It works by stopping the release of certain natural substances that cause pain and swelling.

This medication comes in the form of an eye drop to be given once a day beginning the day before cataract surgery, on the day of surgery, and for 14 days after surgery.

Common side effects in clinical trials include eye pain, eye discomfort in bright light, blurred vision, and the feeling of "something in the eye" (foreign body sensation).

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Bromfenac Cautionary Labels

precautions

Uses of Bromfenac

Bromfenac is a prescription medication used to treat eye inflammation and eye pain in patients who have undergone cataract surgery.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Bromfenac Brand Names

Bromfenac may be found in some form under the following brand names:

Bromfenac Drug Class

Bromfenac is part of the drug class:

Side Effects of Bromfenac

Serious side effects have been reported with bromfenac. See “Drug Precautions” section.

Common side effects in clinical trials include eye pain, eye discomfort in bright light, blurred vision, and the feeling of "something in the eye" (foreign body sensation).

This is not a complete list of bromfenac side effects. Ask your doctor or pharmacist for more information.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Bromfenac Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Bromfenac does not have any listed drug interactions. Ask your doctor or pharmacist for more information.

Bromfenac Precautions

Serious side effects have been reported with Bromfenac including:

  • Sulfite Allergic Reactions: Contains a sulfite that may cause allergic type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in people with this allergy.
  • Slow or Delayed Healing: All topical nonsteroidal anti-inflammatory drugs (NSAIDs), including bromfenac, may slow or delay healing.
  • Potential for Cross-Sensitivity: There is the potential for cross-sensitivity to aspirin and other NSAIDs, including bromfenac. Therefore, caution should be used if you have previously exhibited sensitivities to these drugs.
  • Increased Bleeding Time: With some NSAIDs, including bromfenac, increased bleeding time may be possible, especially when it is given after surgery. Bromfenac should be used with caution in those with known bleeding tendencies or who are receiving blood thinners
  • Keratitis and Corneal (front layer part of the eye) Reactions: Use of bromfenac may result in keratitis (inflammation of the eye). Long-term use of bromfenac may also result in eye damage, leading to loss of sight. Patients with changes in eyesight should immediately discontinue use of topical bromfenac.
  • Loss of sight: Those with complicated ocular surgeries, eye defects or damage, diabetes, eye diseases (such as dry eye syndrome), rheumatoid arthritis, or repeat ocular surgeries within a short period of time may be at increased risk for eye problems which may result in loss of sight. Bromfenac should be used with caution in these patients.
  • Eye Surgery Precaution: Use of bromfenac more than 24 hours before surgery or beyond 14 days after surgery may increase risk for the occurrence and severity of corneal (front layer of the eye) adverse events.

Bromfenac can cause blurred vision. Do not drive or operate heavy machinery until you know how bromfenac affects you.

 

Bromfenac Food Interactions

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of bromfenac, there are no specific foods that you must exclude from your diet when receiving Bromfenac.

Inform MD

Before taking bromfenac, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • have a sulfa allergy
  • have had an allergic reaction to this medication before, to any other NSAID, or to aspirin (Ecotrin)
  • have eye defects, damage, or dysfunction
  • have rheumatoid arthritis
  • have or have had other recent ocular surgeries
  • have diabetes
  • take blood thinners
  • are pregnant or breastfeeding

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

 

Bromfenac and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Bromfenac falls into category C. No studies have been done in animals, and there are no well-done studies in pregnant women. However, NSAIDs (including Bromfenac) are known to cause harm to the baby’s heart (ductus arteriosus). Therefore, the use of bromfenac during late pregnancy should be avoided. Bromfenac should be given to a pregnant woman only if clearly needed.

Bromfenac and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

Caution should be used when bromfenac is given to a nursing (breastfeeding) woman.
 

Bromfenac Usage

Take bromfenac exactly as prescribed.

This medication is to be given once a day starting on the day before cataract surgery, on the day of surgery, and for 14 days after surgery.

Bromfenac may be given along with other ophthalmic (eye) medications. Drops of each medication prescribed should be given at least 5 minutes apart.

Bromfenac should not be given while wearing contact lenses. Remove contact lenses before using bromfenac. The preservative in bromfenac may be absorbed by soft contact lenses. Lenses may be reinserted after 10 minutes following administration of Bromfenac.

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of bromfenac at the same time.

Bromfenac Dosage

Take bromfenac exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

Insert one eye drop into the affected eye once daily. It should be given one day before cataract surgery, on the day of cataract surgery, and for 14 days after cataract surgery.

Bromfenac Overdose

If you take too much bromfenac, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

Other Requirements

Store bromfenac at room temperature.

Keep this and all medicines out of the reach of children.