Binosto

Binosto is used to slow bone loss and increase bone density. Do not lie down for at least 30 minutes after you take Binosto and after you eat your first food of the day.

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Pharmacist Pharmacist Christine Wicke PharmD, BCPS overviews the uses and common side effects of Binosto
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Binosto Overview

Reviewed: January 15, 2013
Updated: 

Binosto is a prescription medication used to treat osteoporosis in men and women. Binosto is in a class of medications called bisphosphonates. It works by preventing bone breakdown and increasing bone density.

Binosto is available as an effervescent tablet form and is taken once a week dissolved in a half glass of water, on an empty stomach.
 
Some common side effects are stomach pain, heart burn, and constipation. 

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Binosto Cautionary Labels

precautionsprecautionsprecautionsprecautions

Uses of Binosto

Binosto is a prescription medicine used to:

  • Treat osteoporosis in women after menopause. It helps reduce the chance of having a hip or spinal fracture (break). Osteoporosis is a disease where your bones become weaker and are more likely to break.
  • Increase bone mass in men with osteoporosis.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Manufacturer

Binosto Drug Class

Binosto is part of the drug class:

Side Effects of Binosto

The most common side effects of Binosto are:

  • Stomach area (abdominal) pain
  • Heartburn
  • Constipation
  • Diarrhea
  • Upset stomach
  • Pain in your bones, joints, or muscles
  • Nausea

You may get allergic reactions, such as hives or, in rare cases, swelling of your face, lips, tongue, or throat.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Binosto may cause serious side effects. See "Drug Precautions."

These are not all the possible side effects of Binosto. For more information, ask your doctor or pharmacist.

Binosto Interactions

Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:

  • antacids
  • calcium supplements
  • aspirin
  • nonsteroidal anti-inflammatory drugs (NSAIDS) like ibuprofen (Advil, Motrin) or naproxen (Aleve)

This is not a complete list of Binosto drug interactions. Ask your doctor or pharmacist for more information.

Binosto Precautions

Binosto can cause serious side effects including:

1. Esophagus problems. It is important that you take Binosto exactly as prescribed to help lower your chance of getting esophagus problems.

  • Stop taking Binosto and call your doctor right away if you get chest pain, new or worsening heartburn, or have trouble or pain when you swallow.
2. Low calcium levels in your blood (hypocalcemia).  Binosto may lower the calcium levels in your blood. If you have low blood calcium before you start taking Binosto, it may get worse during treatment. Your low blood calcium must be treated before you take Binosto. Most people with low blood calcium levels do not have symptoms, but some people may have symptoms. Call your doctor right away if you have symptoms of low blood calcium such as:
  • Spasms, twitches, or cramps in your muscles
  • Numbness or tingling in your fingers, toes, or around your mouth

Your doctor may prescribe calcium and vitamin D to help prevent low calcium levels in your blood, while you take Binosto. Take calcium and vitamin D as your doctor tells you to.

3. Bone, joint, or muscle pain.  Some people who take Binosto develop severe bone, joint, or muscle pain.
 
4. Severe jaw bone problems (osteonecrosis). Severe jaw bone problems may happen when you take Binosto. Your doctor should examine your mouth before you start Binosto. Your doctor may tell you to see your dentist before you start Binosto. It is important for you to practice good mouth care during treatment with Binosto.
 
5. Unusual thigh bone fractures.
Some people have developed unusual fractures in their thigh bone. Symptoms of a fracture may include new or unusual pain in your hip, groin, or thigh.

Call your doctor right away if you have any of these side effects.

Do not take Binosto if you:

  • Have certain problems with your esophagus, the tube that connects your mouth with your stomach.
  • Cannot stand or sit upright for at least 30 minutes.
  • Have low levels of calcium in your blood.
  • Are allergic to Binosto or any of its ingredients.

Binosto Food Interactions

Always take Binosto on an empty stomach. If taken with food or drink (other than water), the body will not be able to absorb and use this medication.

Binosto effervescent tablets contain a high amount of salt in each tablet. Avoid eating foods with a high amount of salt if your doctor has told you to limit how much salt you eat.

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Binosto there are no specific foods that you must exclude from your diet when receiving Binosto.

Inform MD

Before you start Binosto, be sure to talk to your doctor if you:

  • Have problems with swallowing
  • Have stomach or digestive problems
  • Have low blood calcium
  • Plan to have dental surgery or teeth removed
  • Have kidney problems
  • Have been told you have trouble absorbing minerals in your stomach or intestines (malabsorption syndrome)
  • Are pregnant, or plan to become pregnant. It is not known if Binosto can harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if Binosto passes into your milk and may harm your baby.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Certain medicines may affect how Binosto works.

Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist each time you get a new medicine.

Binosto and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

This medication falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Binosto and Lactation

Tell your doctor if you are breastfeeding or planning to breastfeed. It is not known if Binosto is excreted in human breast milk or if it will harm your nursing baby.

 

 

Binosto Usage

  • Take Binosto exactly as your doctor tells you.
  • Binosto works only if taken on an empty stomach.
  • Take Binosto after you get up for the day and before taking your first food, drink, or other medicine.
  • Do not take Binosto at bedtime or before arising for the day
  • Take Binosto while you are sitting or standing.
  • Do not chew or suck on a Binosto tablet.
  • Do not take Binosto with mineral water, coffee, tea, soda, or juice.
  • Choose the day of the week that best fits your schedule.

How to use Binosto effervescent tablets:

  • Dissolve one tablet of Binosto in approximately half a glass of plain room temperature water (4 oz). Wait at least 5 minutes after the effervescence stops, stir the solution for approximately 10 seconds and drink the solution.
  • Swallow solution at least 30 minutes before the first food, beverage, or medication of the day.
  • Do not lie down for at least 30 minutes after you take Binosto and after you eat your first food of the day.
  • If you miss a dose of Binosto, do not take it later in the day. Take your missed dose on the next morning after you remember and then return to your normal schedule. Do not take 2 doses on the same day.
  • If you take too much Binosto, call your doctor. Do not try to vomit. Do not lie down.

Binosto Dosage

Take Binosto exactly as your doctor prescribes it. Follow the directions on your prescription label carefully. The recommended once-weekly dose is 70 mg.

Binosto Overdose

If you take too much Binosto, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If Binosto is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store Binosto at 20°C to 25°C (68°F to 77°F).
  • Keep Binosto and all medicines out of the reach of children.