 is a prescription medication used to treat migraine headaches once they have started. Axert belongs to a group of drugs called serotonin receptor agonists or "Pin It")
Axert Overview
Axert (generic: almotriptan) is a prescription medication used to treat migraine headaches once they have started. Axert belongs to a group of drugs called serotonin receptor agonists or "triptans", which relieve pain by narrowing blood vessels around the brain.
Uses of Axert
Axert is a prescription medication used to treat migraine headaches once they have started, with or without aura.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Side Effects of Axert
The most common side effects in adults are:
- nausea
- sleepiness
- tingling or burning feeling
- headache
- dry mouth
- vomiting
- dizziness
If you experience sleepiness, you should not drive or operate heavy machinery or perform any task that requires mental alertness.
In very rare cases, patients taking this class of medicines experience serious side effects including death. These effects include:
- heart problems
- stroke
- increased blood pressure
Tell your doctor right away if you feel tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw after taking Axert.
Some people may have a reaction called serotonin syndrome, which can be life-threatening, when they use Axert. In particular, this reaction may occur when they use Axert together with certain types of antidepressants known as SSRIs or SNRIs. Symptoms may include:
- mental changes (hallucinations, agitation, or coma)
- fast heartbeat
- changes in blood pressure
- high body temperature or sweating
- tight muscles
- trouble walking
- nausea
- vomiting
- diarrhea.
Call your doctor immediately if you have any of these symptoms after taking Axert.
This is not a complete list of Axert side effects. Ask your doctor or pharmacist for more information.
Axert Interactions
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you take:
- monoamine oxidase (MAO) inhibitors, such as phenelzine sulfate (Nardil) or tranylcypromine sulfate (Parnate) for depression or another condition, or if it has been less than two weeks since you stopped taking an MAO inhibitor.
- ketoconazole (Nizoral), itraconazole (Sporanox), ritonavir (Norvir), or erythromycin (Emycin), or if it has been less than one week since you stopped taking one of these drugs.
- selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), two types of drugs for depression or other disorders. Common SSRIs are Celexa (citalopram HBr), Lexapro (escitalopram oxalate), Paxil (paroxetine), Prozac/Sarafem (fluoxetine), Symbyax (olanzapine/fluoxetine), Zoloft (sertraline), and fluvoxamine. Common SNRIs are Cymbalta (duloxetine) and Effexor (venlafaxine).
These medicines may affect how Axert works, or Axert may affect how these medicines work. This is not a complete list of Axert drug interactions. Ask your doctor or pharmacist for more information.
Axert Precautions
Do not take Axert if you:
- have ever had heart disease.
- have uncontrolled high blood pressure.
- have hemiplegic or basilar migraine. If you are not sure, ask your doctor.
- have taken another serotonin receptor agonist (e.g., another triptan) in the last 24 hours. These include naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, Treximet), or zolmitriptan (Zomig).
- have taken ergotamine-type medicines in the last 24 hours. These include ergotamine (Bellergal-S, Cafergot, Ergomar, Wigraine), dihydroergotamine (D.H.E. 45), or methysergide (Sansert).
- had an allergic reaction to Axert or any of its ingredients. The active ingredient is almotriptan malate. See "Forms of Medication" for inactive ingredients.
Axert Food Interactions
Grapefruit and grapefruit juice may interact with Axert and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
Inform MD
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Before receiving Axert, tell your doctor about all of your medical conditions including:
- past or present medical problems
- past or present high blood pressure, chest pain, shortness of breath, or heart disease
- liver or kidney problems
- high blood pressure
- diabetes
- high cholesterol
- overweight
- smoking
- family members with heart disease
- you are past menopause
- you are a male over 40 years old
- allergic reactions to sulfonamides, also known as sulfa drugs or other allergies
Talk to your doctor about using Axert if you are pregnant, planning to become pregnant, or breastfeeding.
Axert and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if Axert will harm your unborn baby.
Axert and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed. It is not known if Axert is excreted in human breast milk or if it will harm your nursing baby.
Axert Usage
- When you have a migraine headache, take your medicine as directed by your doctor.
- If your headache comes back after your first dose, you may take a second dose 2 hours or more after the first dose. If your pain continues after the first dose, do not take a second dose without first checking with your doctor.
- Do not take more than two Axert Tablets in a 24-hour period.
- If you take too much medicine, contact your doctor, hospital emergency department, or poison control center right away.
Axert Dosage
Take Axert exactly as prescribed. Follow the directions on your prescription label carefully. The maximum recommended daily dose is 25 mg.
Axert Overdose
If you take too much Axert, call your local Poison Control Center or seek emergency medical attention right away.
Forms of Axert
Axert is available as 6.25 mg and 12.5 mg tablets.
Active ingredient: almotriptan
Inactive ingredients: mannitol, powdered cellulose, sodium starch glycolate type A potato, sodium stearyl fumarate, titanium dioxide, hypromelloses, polyethylene glycols, propylene glycol, ferric oxide red, carnauba wax.
Other Requirements
Keep your medicine in a safe place where children cannot reach it. It may be harmful to children. Store your medicine away from heat, light, or moisture at a controlled room temperature. If your medicine has expired, throw it away as instructed. If your doctor decides to stop your treatment, do not keep any leftover medicine unless your doctor tells you to do so. Throw away your medicine as instructed. Be sure that discarded tablets are out of the reach of children.
