Antihemophilic Factor (Recombinant), PEGylated

Controls bleeding in people with hemophilia A. Tell your doctor about all prescription and over-the-counter medications you take.

Antihemophilic Factor (Recombinant), PEGylated Overview

Reviewed: November 17, 2015
Updated: 

Antihemophilic Factor (Recombinant), PEGylated is a prescription medication used to control and reduce the number of bleeding episodes in patients with hemophilia A. Antihemophilic Factor (Recombinant), PEGylated belongs to a group of drugs called clotting factor replacement treatments. These work by replacing clotting factor that is missing in people with hemophilia.

This medication is available as an infusion (goes directly into your bloodstream) by a healthcare professional or in your home after proper training.

Common side effects include headache and nausea.

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Uses of Antihemophilic Factor (Recombinant), PEGylated

Antihemophilic Factor (Recombinant), PEGylated is a prescription medication used to prevent and control bleeding in patients with hemophilia A. Hemophilia A is an inherited bleeding disorder that prevents blood from clotting normally.

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

Antihemophilic Factor (Recombinant), PEGylated Brand Names

Antihemophilic Factor (Recombinant), PEGylated may be found in some form under the following brand names:

Antihemophilic Factor (Recombinant), PEGylated Drug Class

Antihemophilic Factor (Recombinant), PEGylated is part of the drug class:

Side Effects of Antihemophilic Factor (Recombinant), PEGylated

Common side effects include headache and nausea.

This is not a complete list of side effects. Ask your doctor or pharmacist for more information.

Tell your doctor if you have any side effect that bothers you or that does not go away.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Antihemophilic Factor (Recombinant), PEGylated Interactions

No drug interactions have been studied by the manufacturer. However, you should tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Not all drug interactions are known or reported and new drug interactions are continually being reported.

Antihemophilic Factor (Recombinant), PEGylated Precautions

You should not use Antihemophilic Factor (Recombinant), PEGylated if you:

Tell your healthcare provider if you are pregnant or breastfeeding because Antihemophilic Factor (Recombinant), PEGylated may not be right for you.

Antihemophilic Factor (Recombinant), PEGylated Food Interactions

Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Antihemophilic Factor (Recombinant), PEGylated, there are no specific foods that you must exclude from your diet when receiving this medication.

Inform MD

Before taking Antihemophilic Factor (Recombinant), PEGylated, tell your doctor about all of your medical conditions. Especially tell your doctor if you:

  • are allergic to Antihemophilic Factor (Recombinant), PEGylated or to any of its ingredients
  • have or have had any medical problems
  • have any allergies, including allergies to mice or hamsters
  • are breastfeeding
  • are pregnant or plan to become pregnant
  • have been told that you have inhibitors to factor VIII (because Antihemophilic Factor (Recombinant), PEGylated may not work for you)

Tell your doctor about all medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Antihemophilic Factor (Recombinant), PEGylated and Pregnancy

Tell your doctor if you are pregnant or plan to become pregnant.

There are no studies that have been done in humans or animals with Antihemophilic Factor (Recombinant), PEGylated. It is not known if Antihemophilic Factor (Recombinant), PEGylated can harm an unborn baby. Antihemophilic Factor (Recombinant), PEGylated should only be used in pregnant women if it is clearly needed.

Antihemophilic Factor (Recombinant), PEGylated and Lactation

Tell your doctor if you are breastfeeding or plan to breastfeed.

It is not known if Antihemophilic Factor (Recombinant), PEGylated crosses into human milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants with use of this medication, a choice should be made whether to stop nursing or stop the use of this medication. Your doctor and you will decide if the benefits outweigh the risk of using Antihemophilic Factor (Recombinant), PEGylated.

Antihemophilic Factor (Recombinant), PEGylated Usage

This medication comes as a dry powder to be mixed into a solution and injected into a vein (IV) by a healthcare provider. Many people with hemophilia A learn to infuse their Antihemophilic Factor (Recombinant), PEGylated by themselves or with the help of a family member.

Do not attempt to do an infusion to yourself unless you have been taught how by your healthcare provider or hemophilia center.

You must carefully follow your healthcare provider’s instructions regarding the dose and schedule for infusing Antihemophilic Factor (Recombinant), PEGylated so that your treatment will work best for you.

You may have to have blood tests done after receiving Antihemophilic Factor (Recombinant), PEGylated to be sure that your blood level of factor VIII is high enough to clot your blood.

Call your healthcare provider right away if your bleeding does not stop after taking Antihemophilic Factor (Recombinant), PEGylated.

Antihemophilic Factor (Recombinant), PEGylated Dosage

Take this medication exactly as prescribed by your doctor. Follow the directions on your prescription label carefully.

The dose your doctor recommends may be based on the following:

  • the condition being treated
  • other medical conditions you have
  • other medications you are taking
  • how you respond to this medication
  • your weight
  • your height
  • your age

Your healthcare provider will tell you how much Antihemophilic Factor (Recombinant), PEGylated to use based on your weight, level of physical activity, the severity of your hemophilia A, and where you are bleeding.

Antihemophilic Factor (Recombinant), PEGylated Overdose

If you take too much Antihemophilic Factor (Recombinant), PEGylated, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away.

If Antihemophilic Factor (Recombinant), PEGylated is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.

Other Requirements

  • Store Antihemophilic Factor (Recombinant), PEGylated in the refrigerator and do not freeze.
  • Antihemophilic Factor (Recombinant), PEGylated may be stored at room temperature for up to one month. After storage at room temperature, do not return Antihemophilic Factor (Recombinant), PEGylated back to the refrigerator.
  • Do not use beyond the expiration date printed on the carton or vial.
  • Store vials in their original box and protect them from extreme exposure to light.
  • Always check the actual dosage strength printed on the label to make sure you are using the strength prescribed by your healthcare provider.
  • Dispose of all materials, including any leftover reconstituted (after mixing dry product with wet diluent) Antihemophilic Factor (Recombinant), PEGylated, in an appropriate container.
  • Reconstituted product must be used within 3 hours and cannot be stored or refrigerated.
  • Keep this and all medicines out of reach of children.